Overview:  Research led by Dr. Justin Lee recently published in the Canadian Medical Association Journal (CMAJ) Open determined the financial contribution of medications to health care users (HCU) expenditures and explore whether potentially inappropriate prescribing is associated with incident HCU development.


ClinicalTrials.gov Identifier: NCT02815930
Study Type: Observational
Participants (N): 7000
Observational Model: Cohort (Retrospective)
Intervention Description: This cohort was matched to a cohort of non-HCUs using a 3:1 matching ratio (non-HCU to HCU) based on age at cohort entry (+/- 1 month), sex and geographic location of residence (based on LHIN) for comparative analysis. Descriptive statistics were used to describe the study populations and outcomes. Regression analyses was used to adjust for potential confounders when analyzing healthcare resource utilization and costs as a function of HCU status (e.g. income, type of residence, co-morbidities, rural/urban) and/or when analyzing sub-populations [e.g. chronic obstructive pulmonary disease (COPD), congestive heart failure (CHF)]. Logistic regression was performed using the patient level data to predict the impact of individual factors on the likelihood of becoming a senior HCU.