Overview: COMPASS-ND is the signature clinical study of The Canadian Consortium on Neurodegeneration in Aging (CCNA). The COMPASS-ND Study is an observational study of people with various types of dementia or cognitive complaints. The study collected clinical, neuropsychological, and MRI imaging data as well as blood, saliva, and urine samples from participants.


Large-scale Alzheimer’s Disease and Dementia Research Study

The goals of COMPASS-ND are to:

  • Detect dementia earlier
  • Make diagnosis of dementia easier
  • Predict who is at risk for developing dementia

Summary: Up to now, most studies of age-related cognitive decline have focused on specific types of dementia in isolation. The goal of COMPASS-ND is to study dementia in all its forms, including cases where there are multiple pathologies involved, such as Alzheimer’s disease and cerebrovascular disease, referred to as “mixed” dementia. This broad approach is being taken in order to investigate what these dementias have in common, as well as what differentiates them. Doing so will help in diagnosing, understanding, and working to prevent the onset of dementia in all its forms. In the case of mixed dementia, study results will help CCNA researchers examine the impacts of different pathologies alone and in combination, and their implications for disease course and treatment.